By metro: Metro 51, 53 and 54 (stop Waterlooplein)
By tram: Trams 4, 9 and 14 (stop Rembrandtplein)
More information about public transport in Amsterdam: www.gvb.nl
By car: From the A10: follow signs for S100, exit 'Centrum', follow P signs. The nearest underground parking facility is 'Stadhuis/Muziektheater' at Waterlooplein.
Museum Willet-Holthuysen is an old canal house, without an elevator. Access for wheelchair users is therefore not possible unfortunately.